Japan startup eyes clinical trials for stem cell-based diabetes treatment

Japan startup eyes clinical trials for stem cell-based diabetes treatment

Biotechnology

Orizuru Therapeutics seeks breakthrough to reduce insulin doses for Type 1 patients

Orizuru Therapeutics looks to process pancreatic islet cells created from iPS cells into sheets and transplant them into patients with Type 1 diabetes. (Orizuru Therapeutics)

NORIYUKI TAKADA, HINAKO BANNO and TAITO KUROSE

TOKYO — Japanese biotech startup Orizuru Therapeutics will start clinical trials as soon as fiscal 2027 for a diabetes treatment using induced pluripotent (iPS) stem cells that could reduce insulin doses needed to lower blood sugar levels, potentially transforming the way the disease is treated.

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